Hubert H. Lim, Ph.D.
Institute for Translational Neuroscience Scholar
Department of Biomedical Engineering
Department of Otolaryngology, Head and Neck Surgery
Director of SONIC Lab
Chief Scientific Officer
Neuromod Devices Limited - link
Chief Scientific Officer
SecondWave Systems - link
The goal of the lab is to push the development and translation of neural interfaces and medical technologies from scientific concept into clinical application with close collaboration with clinicians and industry. Initial medical applications focus on treating hearing loss, tinnitus and pain. We utilize a range of invasive and noninvasive technologies and approaches including electrical stimulation, ultrasound imaging and stimulation, EEG, and invasive neural recordings in animals and humans to rapidly push technology into the clinical and consumer realm. All projects in the lab follow the translational process depicted in the schematic below. The lab consists of both animal facilities and human testing space to perform proof-of-concept experiments that can then be developed and tested in pilot human studies, followed by further scientific and translational research to achieve confirmatory clinical trials and commercialization.
The SONIC Lab is pursuing a range of neural engineering and clinical topics. Please click on the images below for further details on each project.
Please click on research image for further details
- 12/20 - An incredible podcast episode on Skraps with Arun Sridhar and JoJo Platt interviewing Dr. Lim on his career pathway since undergraduate to his current faculty. They touch on different projects, personal experiences, and lots of interesting topics!
- 12/20 - Listen to Dr. Lim talk with the American Tinnitus Association on their podcast about the recent bimodal sound and tongue stimulation for tinnitus that was published in Science Translational Medicine.
- 11/20 - Check out the highlights for the tinnitus trestment research in JAMA and Nature Med!
- 10/20 - See and hear Dr. Lim discussing with David Stockdale, Chief Executive of British Tinnitus Association, about the tinnitus treatment results using bimodal neuromodulation with sound and tongue stimulation that was recently published in Science Translational Medicine.
- 10/20 - Check out the latest translational research by many key leaders in the tinnitus field together with Dr. Hubert Lim through his involvement with Neuromod Devices that was featured in the cover of Science Translational Medicine for their recent publication (paper). The paper describes the largest and longest follow-up clinical study for a medical device that treats tinnitus, which uses bimodal neuromodulation combining sound and tongue stimulation. The SONIC lab dedicated many years in pre-clinical animal research on bimodal neuromodulation to help push this concept to human studies. Excited to see the press coverage of the work, including in the Science podcast, Hearing Health Matters, MedTech News, Neuro News, Pharmaceutical Daily, Wall Street Online, Scientific American, Science Magazine, New Scientist, and IEEE Spectrum.
- 07/20 - Incredible new paper coming from our lab that has recently been submitted for publication. Checkout this preprint on using ultrasound to reduce inflammation, and potentially use this technology for the treatment of COVID-19.
- 06/20 - Research between SONIC Lab and SecondWave Systems may prove effective in a noninvasive treatment for COVID-19. Check out an exciting article on how the SONIC Lab is helping combat the pandemic.